Connecting with PySerial requires a reset

Hi! Thanks for reading.

I'm controlling the BlackBox via Python and PySerial on Raspberry Pi (Raspberry Pi OS). It works great. One problem I have and can't figure out is why I have to press the Reset button to get the script to work a second time. I have used this code on another controller board and I don't have this problem. When I connect to the Black Box via CuteCom or Arduino IDE Serial monitor, i don't have the problem. I feel like these programs are doing something to properly close the connection I'm not. Below is a sample script I've been using for testing purposes.

If I use one of these terminal emulators to open and close the serial connection, then I am able to reconnect via PySerial.

Thanks for any help.

Code:

import serial
import time

dev = serial.Serial('/dev/ttyUSB0', 115200, timeout=2)
time.sleep(2)

while(True):  
    response = dev.readline().decode('utf-8').strip()
    print(response)
    uin = input("> ")
  
    if(uin == "quit"):
        dev.close()
        exit()
  
    uinb =  bytes(uin, 'utf-8')
    dev.write(uinb)
  
    time.sleep(1)